Manager Gary Hackett made three changes from Tuesday night's defeat at Witton Albion, with Jordan Fitzpatrick, Reece Hales and the injured Chris Knight replaced by Drew Canavan, Will Richards and Kayelden Brown. Luke Benbow started in attack as a lone striker.
There were early chances for the Glassboys as Leon Miles headed wide from Leon Broadhurst's corner on 8 minutes and then 3 minutes later a through ball put Brown clear down the right only for a poor first touch to give Blyth keeper Nick Thomson the opportunity to come off his line and smother the chance.
Two minutes later, Blyth were awarded a penalty when Dan Maguire broke clear only for the onrushing Dean Coleman to bring him down. There seemed little doubt about the decision but Robbie Wade was less emphatic with his finish from the spot, blazing the ball well over Coleman's crossbar.
The let-off proved short-lived, however. Blyth had already come close again on 19 minutes when Maguire's shot from the edge of the box took a wicked deflection and drifted just wide of the post with Coleman left stranded heading in the opposite direction, but they were to break the deadlock with just 3 more minutes on the clock.
Tyrone Williams was turned too easily 25 yards from goal, and brought down the lively MaGuire, giving Stephen Turnbull the opportunity to curl his free-kick round the Stourbridge wall and just inside the near post with the unsighted Coleman rooted to the spot.
Coleman saved well from Jarrett Rivers on the half-hour, before the busy Brian Smikle was unlucky with his volley from Brown's cross on 32 minutes as Thomson beat the effort away, and then Richards saw his low shot held comfortably by Thomson just before the break.
Stourbridge will have felt they were in the game at the interval, but Blyth were to take control as the second half progressed. There was a scare on 49 minutes as Michael Richardson picked up Broadhurst's loose clearance only to drag his shot wide of the upright, and a minute later Maguire put the ball in the net only to be denied by an offside flag.
But a second goal did come after 52 minutes when Dale's cross-field ball found Rivers, who cut in from the flank and fired a low shot inside Coleman's near post from the edge of the area, with the Glassboys' keeper perhaps a little slow to react.
Stourbridge pushed forward looking for a way back into the game, but chances were few and far between against a resilient and well-organised Blyth back-line. Smikle's low cross cum shot was cleared off the line on 73 minutes but that was as close as the Glassboys came to reducing the deficit.
And Blyth sealed the points with 10 minutes on the clock as substitute Dan Hawkins beat the offside trap to run onto Richardson's through ball to slide a confident finish low under Coleman.
There was time for Coleman to deny Blyth a fourth in stoppage time with a save from Hawkins, but the game had been settled long before then.
The result means that Stourbridge remain 13th in the Premier Division table.
Stourbridge: Coleman, Smikle, Canavan, Williams, Richards (Morgan-Parker 57), Miles, Connolly, Broadhurst (Quaynor 74), Benbow, Lait (Fitzpatrick 74), Brown.
Unused substitutes: Hales, Wint.
Attendance: 384.